叔丁基杯[6]芳烃的去叔丁基反应

De-tert-butylation Reaction of Tert-butylcalix[6]arene

报道了以对叔丁基杯[6]芳烃为原料，室温时，在三氯化铝催化下选择性脱去叔丁基的工艺．探讨了在合成去叔丁基杯[6]芳烃实验中催化剂用量对反应结果的影响，并对反应机理进行了讨论．结果表明，当n（AlCl3）：n（p-tert-calix[6]arene）=8～9．5：1时，分离得到了两种去叔丁基杯[6]芳烃：5-叔丁基-37，38，39，40，41，42-六羟基杯[6]芳烃和37，38，39，40，41，42-六羟基杯[6]芳烃，当n（AlCl3）：n（p—tert-calix[6]arene）=10．5：1时，得到37，38，39，40，41，42-六羟基杯[6]芳烃，产率90．8％．

The selective de-tert-butylation of p-tert-butyl calix[ 6] arene with AICl3 at ambient temperature has been investigated. The effect of catalyst quantity was discussed on the basis of reaction mecha- nism. Mono-p-tert-butylc-alix[ 6] arene and de-tert-butyl calix[ 6] arene were obtained, when p-tert-butyl calix[ 6] arene was treated with 8 - 9.5 equivalents of AlCl3. De-tert-butyl calix[ 6] arene was exclusively obtained in yield of 90.8 % when 10.5 equivalents of AlCl3 was used at ambient temperature.