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华支睾吸虫病患者血清sVCAM-1水平的动态观察

The kinetic observation of sVCAM in the serum of patients with clonorchiasis
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摘要 目的:探讨华支睾吸虫病患者可溶性血管内皮细胞粘附分子(sVCAM-1)和白细胞介素4(IL-4)水平的变化及临床意义。方法:采用双抗体夹心EL ISA法、放射免疫法,分别检测患者血清中sVCAM-1和IL-4的含量。结果:华支睾吸虫病患者sVCAM-1和IL-4的水平明显增高,与对照组相比有显著差异(P<0.01)。结论:sVCAM-1和IL-4通过多种免疫调控作用,参与了华支睾吸虫病的发病过程。 Objective.To explore the changes in the levels of soluble vascular cell adhesion molecule-1 （sVCAM-1）and their clinical significance in patients with clonorchiasis. Methods ：sVCAM-1 and IL-4 were examined by radioimmunoassay （RIA） and enzyme- linked immunosorbent assay （ELISA）. Results ： The levels of sVCAM-1 and IL-4 in patients with clonorchiasis were significantly higher than those of the control group,with a significarit difference （P 〈 0.01）. Conclusion.sVCAM-1 and IL-4 participate in the process of clonorchiasis by several immunoregulation ways.
作者 蔡连顺 王树清 肖景莹 毕胜 车世伟 代月
机构地区 佳木斯大学基础医学院 佳木斯市中心医院检验科
出处 《黑龙江医药科学》 2007年第1期3-4,共2页 Heilongjiang Medicine and Pharmacy
基金 黑龙江省卫生厅资助项目(No.2004-003)佳木斯大学资助项目(2002-12)
关键词 华支睾吸虫病 可溶性血管内皮细胞粘附分子 白细胞介素4 clonorchiasis soluble vascular cell adhesion molecule- 1 （sVCAM - 1 ） interleukin- 4
分类号 R383.22 [医药卫生—医学寄生虫学]
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参考文献10

  • 1康庆德,魏庆云,谢秀兰,吴丽萍,张卓,付艳华,季光协,马全海,宋子云,王德冲.黑龙江人体寄生虫分布调查结果的分析[J].中国寄生虫学与寄生虫病杂志,1994,12(S1):71-74. 被引量：10
  • 2王莲芸,王怀云,赵嘉惠,张克军,王宁,乔中东.支气管哮喘患者sVCAM-1和ECP的分析[J].上海免疫学杂志,2000,20(5):311-312. 被引量：1
  • 3曹国强,崔社怀,吴奎,林海龙,毕玉田,杨肇亨.哮喘患者血清可溶性E选择素、血管细胞黏附分子1浓度的变化[J].中国现代医学杂志,2004,14(22):52-54. 被引量：5
  • 4Nagata M,Sedgwick JB,Kita H,et al.Granulocyte macrophage colony-stimur augmentslCAM-1 and VCAM-1 activation of eosiphil function[J].Am J Respir Cell Mol Biol,1998,19:158-164
  • 5Hyodo I,Jinno K,Tanimizu M,et al.Serum intercellular adhesion molecule-1 levels in churonic hepatitis C:association with disease activity and response to interferona[J].Gut,1995,36(4):599
  • 6卢玉莲,崔徵,蒋丽,郝淑维.可溶性粘附分子与妊娠高血压综合征[J].国外医学（妇产科学分册）,2002,29(1):21-23. 被引量：14
  • 7Brogdon Jennifer L.I.eitenberg David,Bottomly Kim.The potency of TCR signaling differentially regulates NFATc/p ctivity andearly IL-4 transcription in naive CD4+T cells[J].Journal of immunology,2002,168:3825-3832
  • 8Yamazaki Fumie,Aragone Yoshinori。Maeda Akira,et al.Overactivation of IL-4 induced aetivator protein-1 in atopic dermatitis[J].Journal of Dermatological Science,2002,28:227-233
  • 9Khayyamian Saman,Huttoff Andreas,Buchner Kerstm,et al.ICOS-ligand,expressed on human endothelial cells,costimulates Th1 and Th2 cytokine secretion by memory CD4+T cells[J].Proceedings of the National Academy of Sciences of the United States of America,2002,99:6198-6203
  • 10Penna A,Del Prete G,Cavalli A,et al.Predominant T-helper 1 cytokine profile of hepatitis B virus nucleocapsid-specific Tcells in acute self-limited hepatitis B[J].llepatology,1997.25:1022-1027

二级参考文献35

  • 1Zhou Y,Daesky CH,Fish.Preeclaepsia is associated with failure of human cytotrphoblasts to mimic a vascular adhesion phenotype.J Clin Invest,1997,99:2152-2164
  • 2Zeisler H,Livingston JC,Schatton C,et al.Wien Klin Wochensche,2001,113:588-592
  • 3Labarrere LA,Faulk WP.Intercellular adhesion molecule-1 (ICAM-1)and HLA-DR antigens are expressed on endovascular cytotrophoblasts in abnormal pregnancies.Am J Reprod Immunol,1995,33:47-53
  • 4Airoldi L,Gaffuri B,Rossi G,et al.Soluble intercellular adhesion molecule-1 serum profile in physiologic and preeclamptic pregnancy.Am J Reprod Immunol,1998,39:183-188
  • 5Djurovic S,Schjetlrin R,Wisloff F,et al.Increased levels of intercellu lar adhesion molecule and vascular cell adhesion molecule in preeclampsia.Br J Obstet Gynaecol,1997,104:466-470
  • 6Phocas Ⅰ,Rizos D,Papoulias J,et al.A comparative study of serum soluble vaseuler cell adhesion molecule-1 and soluble intercellular adhesion molecule-1 in preeclampsia.J Perinatology,2000,2:114-119
  • 7Heyl W,Handt S,Reister F,et al.Elevated soluble adhesion molecules in women with pre-eclampsia.Eur J Obstet Gynecol Reprod Biol,1999,86(1):35-41
  • 8Heyl W,Handt S,Reister F,et al.The role of soluble adhesion molecules in elevating endothelial cell activation in preeclampsia.Am J Obstet Gynecol,1999,180:68-72
  • 9Daniel Y,Kupfermil MJ,Baram A,et al.A selective increase in plasma soluble VCAM-1 levels in preeclampsia.Am J Reprod Immunol,1999,41:407-412
  • 10Knorr R,Dustin ML.The lymphocyte function associated antigen (LFA)-1 I domain is a transient binding molecule for intercellular adhesion molecule (ICAM-1) and ICAM-3 in hydrodynamic flow.J Exp Med,1997,186:719-730

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黑龙江医药科学
2007年 第1期

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