宫颈癌194例回顾性分析

Age and clinical progrosis：analysis of their association in 194 cases ofcervical cancer

目的探讨宫颈癌的发病年龄与临床特点及病理类型的关系。方法宫颈癌患者194例，分为年轻组（≤35岁）和中老年组（〉35岁）组，进行临床特点分期，病理类型及细胞分化等临床资料对比分析。结果两组患者在临床特点、病理类型差异有统计学意义。≤35岁组临床表现以接触性阴道流血为主；≤Ⅱa期占94．7％，≥Ⅱb期占5．3％；鳞癌占89．5％，腺癌占10．59％，其他类型占0。〉35岁组临床表现以不规则阴道流血和绝经后出血为主；≤Ⅱa期占87．7％，≥Ⅱb期占12．3％；鳞癌占90．4％，腺癌占7．5％，其他类型占2．1％。结论〉35岁组临床期别较高，预后不良。≤35岁组临床期别较低，但腺癌较多。

Objective To investigate the relationship between the patient＇s age and clinical findings and progrosis of cervical cancer. Methods One hundred ninety-four patients with cervical cancer seelected from those hospitalized in Municipal Central Hospital of Huizhou form December 1995 to December 2005 were divided into younger age group（ ≤35 years old）and elder age group（ 〉 35 years old）. Comparison was made in the clinical stages, pathological grade and differentiation between the 2 groups. Results Statistical differerce was found in the clinical findings and stage and pathological grade. The clinical findings in patients below the age of 35 3,ears were postcoital bleeding. 94.7 % were below stage,≤Ⅱ a, and 5. 3 % were above stage ≥Ⅱb. 89.5 % had squamous cell carcinoma and 10.59 % has adnocarcinoma. The clinical findings in patients above the age of 35 years were abnormal bleeding especially after menopause. 87.7% were below stage ≤Ⅱ a,and 12.3 % were.above stage ≥ Ⅱb,90.4% had squamous cell carcinoma and 7.5 % has adnocarcinoma. However, no statistical difference was found in the cell differentiation between the two groups, conclusion Patients above 35 years have poorer progrosis than their younger counterparts which might be due to more advanced clinical stage.