摘要
目的 探讨高频电刀宫颈环形切除术（LEEP）治疗宫颈上皮内瘤样病变（CIN）的效果。方法 回顾分析2000年6月至2005年3月在中国医学科学院肿瘤医院妇科因患CINⅠ～Ⅱ行高频电刀宫颈环状切除术（LEEP）的149例病人临床资料。结果 本研究149例CINⅠ～Ⅱ病人，术前后病理诊断符合率50．3％（75／149），升级20．8％（31／149），降级28．9％（43／149）。剔除因LEEP术后为原位癌及浸润癌而行再次手术的9例病人，治愈123人（87．9％），复发17人（12．1％）。复发与术后病理切缘是否受累有关，与病变级别无关。结论 LEEP术治疗CINⅠ～Ⅱ病变是适宜的，阴道镜检查直视下活检，如病理证实为CINⅠ～Ⅱ者，应行LEEP术，避免早期宫颈癌漏诊。
Objective To evaluate the effectiveness and recurrence factors of loop electrosurgical excision procedure （LEEP） for the management of cervical intraepithelial neoplasia （ CIN Ⅰ -Ⅱ ）. Methods A retrospective analysis was performed of 149 CIN Ⅰ -Ⅱ cases treatment by LEEP. The patients with abnormal cytology were referred for further biopsy under colposcopy evaluation and endocervical curettage （ECC）. Results The coincidence rate of pathologic diagnosis was 50. 3% （75/149）, going up was 20. 8% （31/149）, downgrade was 28.9% （43/149）. To reject nine patients because they received another operation, the cure rate was 87.9% （123/140）, recurrence rate was12. 1 （17/140）. The recurrence had something to do with edge and had nothing to do with pathologic grade. Concision LEEP is the suitable management for CIN Ⅰ - Ⅱ. There were to avoid missed diagnosis of earlier cervical cancer.
出处
《癌症进展》
2007年第1期104-107,共4页
Oncology Progress
