1Von Wartburg A,Traber R.Cyclosporins,fungal metabolites with immunosuppressive activities[J].Prog Med Chem,1988,25:1.
2Wenzel-Seifert K,Seifert R.Cyclosporin H is a potent and selective formyl peptide receptor antagonist.Comparison with N-t-butoxycar bonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L-phenylalanine and cyclosporins A,B,C,D,and E[J].J Immunol,1993,150:4591.
3Loor F,Tiberghien F,Wenandy T,et al.Cyclosporins:structureactivity relationships for the inhibition of the human FPR1 formylpeptide receptor[[J].J Med Chem,2002,45:4613.
4Amato d P,Nunzia M,Nella P,et,al.Urokinase Induces Basophil Chemotaxis through a Urokinase Receptor Epitope That Is an Endogenous Ligand for Formyl Peptide Receptor-Like 1 and -Like 2[J].J Immunol,2004,173:5739.
5Ronghua S,Pablo I,Ning Z,et,al.Identification of Neutrophil Granule Protein Cathepsin G as a Novel Chemotactic Agonist for the G Protein-Coupled Formyl Peptide Receptor[J].J Immunol,2004,173:428.
6Amato de P,Nella P,Isabella F,et,al.Basophils Infiltrate Human Gastric Mucosa at Sites of Helicobacter pylori Infection,and Exhibit Chemotaxis in Response to H.pylori-derived Peptide Hp(2-20)[J].J Immunol,2004,172:7734.
7Potter B,Palmer Rex A,Withnall R,et al.Two new cyclosporin folds observed in the structures of the immunosuppressant cyclosporin G and the formyl peptide receptor antagonist cyclosporin H at ultra-high resolution[J ].Org Biomol Chem,2003,1:1466.
8Ye Zhou,Xiuwu Bian,Yingying Le,et,al.Formylpeptide Receptor FPR and the Rapid Growth of Malignant Human Gliomas[J].Journal of the National Cancer Institute,2005,11:823.
5Deng X Y, Ueda H, Su S B, et al. A synthetic peptide derived from human immunodeficiency virus type 1 gp120downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled rec
6Bylund J, Karlsson A, Boulay F, et al. Lipopolysaccharideinduced granule mobilization and priming of the neutrophil response to Helicobacter pylori peptide Hp(2-20), which activates formyl peptide receptor-like 1. Infect Immun, 2002,70(6): 2908～2914
7Chen X, Mellon R D, Yang L, et al. Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants. Biochem Pharmacol, 2002,63:533～541
8Mills J S, Miettinen H M, Cummings D, et al. Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phc and Met-Met-Trp-Leu-Leu. J Biol Chem, 2000, 275(50):39012～39017
9Shen W P, Proost P, Li B Q, et al. Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines. Biochem Biophys Res Commun, 2000, 272:276～283
10Le Y Y, Gong W H, Li B Q, et al. Utilization of two seventransmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activatio n. J Immunol, 1999, 163:6777
