卵母细胞成熟过程中线粒体的变化

Changes of Mitochondria during the Maturation of Oocytes

卵子成熟是一个复杂的过程,细胞核成熟和细胞质成熟必须和谐的统一在一起,才能保证卵子的正常受精和进一步的发育。作为细胞质内最重要的细胞器,线粒体的分布在卵子成熟过程中出现了显著变化。同时其产生的ATP是卵子、受精卵以及胚胎主要的能量来源。因此,对卵子成熟过程中线粒体的分布和功能变化的研究,有利于进一步了解生殖生理,并为解决辅助生育技术中所面临的难题提供新的思路。

The maturation of oocyte is a complex progress. The nuclear and cytoplasmic maturation should be weU-orchestrated in order to guarantee normal fertilization and further development. Mitochondria are the most important organelles in the cytoplasm and the distribution of which changes dramatically during maturation of oocyte. Meanwhile, the ATP generated by mitochondria is the main resource of energy for oocyte, zygote and embryo. Therefore, researches on the changes of distribution and function of mitochondria during maturation of oocyte will not only be helpful to understand reproductive physiology, but also provide new insights to resolve the problems to be faced with assisted reproductive technology.