高血压合并急性心肌梗死患者脉压的临床研究

Clinical study of pulse pressure in acute myocardial infarction patients with Hypertension

目的探讨脉压水平与冠脉病变程度及急性心肌梗死的关系。方法经冠脉造影确诊冠心病300例,男221例,女79例,年龄(63.92±10.74)岁。外周肱动脉压力测定收缩压、舒张压。冠脉病变严重程度用冠脉病变的血管支数表示。根据WHO标准诊断急性心肌梗死。结果急性心肌梗死患者脉压水平明显高于未发生急性心肌梗死的患者(P<0.05);脉压≥60mmHg的冠心病患者2支和3支病变发生率明显高于脉压<60mmHg的冠心病患者(P<0.05)。结论高血压病合并急性心肌梗死患者脉压差越大,冠脉病变越严重,越容易发生急性心肌梗死。

Objective To evaluate the relationship of the pulse pressure to coronary artery disease. Methods 300 patients was diagnosed by coronary angiography,221 male patients,79 female patients, mean age 30 - 82 （63.92 ± 10. 74）years old. Brachial systolic and diastolic blood pressure were measured. Acute myocardial infarction was diagnosed by WHO criterion. The severity of coronary arterty disease was shown as the number of diseased arteries. Results Patients with acute myocardial infarction had higher pulse preesure than those without acute myocardial infarction （P 〈0.05） ：Compared to patients with pulse pressure 〈60mmHg. patients with pulse pressure≥ 60 mmHg had higher incidence of 2 or 3 coronary artery disease（ P 〈 0.05 ）. Conclusion In acute myocardial infarction patients with Hypertension, the higher pulse pressure, tbe more severe coronary artery diseased and these patients tend to have acute myocardial infarct/on. [Key Words]