雅施达协助心房颤动复律的临床观察

Clinical observation of the effects of perindopril in improving amiodarone's restoring normal rhythm of the heart of constant atrial fibrillation

目的观察雅施达改善胺碘酮对持续性心房颤动的转律效果。方法持续性心房颤动病人78例,口服胺碘酮0.6g/d,疗程2周。随机分为2组,即雅施达组和非雅施达组,观察转律成功率和转律成功所需时间。结果雅施达组胺碘酮转律成功率70.5%(24/34),显著高于非雅施达组42.1%(16/38,P<0.05);雅施达组转律平均时间为(9.1±0.35)d,显著少于非雅施达组(11.7±0.47)d(P<0.01)。结论对持续性心房颤动病人进行胺碘酮转律治疗,加用雅施达可提高转律成功率,缩短转律所需时间。

Objective To investigate the effects of perindopril in improving amiodarone＇s restoring normal rhythm of the heart of constant atrial fibrillation. Methods 78 constant atrial fibrillation patients were divided randomly into perindopril group or non-perindopril group. The restoring success rate and the restoring time of two groups were observed. Results The restore success rate of amiedarone in perindopril group was 70. 5% （24/34）, which is obviously higher than non - perindopril group＇s 42.1% （ 16/38 ,P 〈0.05 ）. The average restoring time in perindopril group was （9. 10 ± 0.35 ） days, which was obviously shorter than non-perindopril group＇s （ 11.70 ± 0.47 ） days （ P 〈 0.01 ）. Conclusion Perindopril can assist amiodarone in restoring normal rhythm of the heart of constant atrial fibrillation , improving the restoring success rate and shortening the average restoring time.