摘要
通过3-氨基-二氢噻吩-2-酮(DL-高半胱氨酸硫内酯)盐酸盐与取代苯甲醛反应,得到3-氨基-二氢噻吩-2-酮类Schiff碱.合成了9个化合物,其中7个为首次报道的新Schiff碱类化合物.化合物结构经IR,1HNMR和元素分析证实,并对这些化合物进行了室内毒力测试,结果表明此类化合物具有很好的杀菌、抑菌活性.
Nine Schiff bases of 3-amino-dihydrothiophene-2-one were synthesized by reaction of substituted benzaldehyde with DL-homocysteine thiolactone hydrochloride by means of preferable reaction conditions. Seven of them were reported for the first time. The structures of the compounds were confirmed by elemental analysis, ^1H NMR and IR spectra. The biological tests showed that they were excellent biological active to several vegetable pathogen.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2007年第1期82-86,共5页
Chinese Journal of Organic Chemistry
基金
陕西省自然科学基金(No.2001H11)
西北大学科研启动基金资助项目.
