非普拉宗和萘普生止痛作用的比较

Feprazone vs naproxen in analgesia

目的：比较非普拉宗与萘普生止痛的疗效。方法：１０８例外科病人随机分为非普拉宗组５４例（男性３６例，女性１８例；年龄４７±ｓ１５ａ），剂量０．２ｇ，ｐｏ，ｂｉｄ；萘普生组５４例（男性３７例，女性１７例；年龄４６±１５ａ）．剂量０．２ｇ，ｐｏ，ｂｉｄ．均服１８ｄ。结果：非普拉宗组止痛总有效率８３％，萘普生组７４％（Ｐ＞０．０５）。不良反应发生率非普拉宗组７％，显著低于萘普生组的２４％，且反应轻微。结论：非普拉宗止痛效果近于萘普生，而不良反应明显较萘普生少而轻。

AIM :To compare the effects of feprazone with naproxen on pain. METHODS:One hundred and eight patients suffering from pain were divided equally into 2 groups at random. The first group(M36,F18,age 47±s 15a)received feprazone 0.2g,po,bid,for 18 d.The other group(M 37,F 17,age 46 ±15a) received naproxen 0.2g,po,bid,for 18 d as control. RESULTS:The clinical total effective rate of feprazone group was 83%,similar to that(74%) of naproxen group(P>0.05). Adverse reactions of feprazone group were fewer than those of naproxen group(7% vs24%,P<0.05).CONCLUSION:Feprazone is similar to naproxen in analgesic effects. Adverse reactions of feprazone are less and milder than those of naproxen.