摘要
目的:评价异帕米星对尿路感染的疗效。方法:尿液细菌培养证实有感染者26例(男性4例,女性22例,年龄53±s14a)。用异帕米星400mg,im(6例静脉滴注)qd,疗程8±3d,根据症状、体征、临床检验及细菌学检查4项判断疗效分痊愈、显效、进步和无效。测定异帕米星药物用MH培养基及KB法。结果:总有效率88%,细菌清除率80%。1例用药后腹胀,局部注射部位疼痛;2例用药后尿素氮轻度升高。结论:异帕米星治疗尿路感染有效,不良反应轻。
AIM:To observe the therapeutic effect of isepamicin on urinary tract infection (UTI) .METHODS:Twenty-six patients(M4,F 22,age 53±s 14 a) with UTI were received isepamicin at a dose of 400 mg/d,im,qd(6 patients iv,gtt)for 5-15 d.Evaluations of clinical effects were done from the symptoms,sign,laboratory findings and the elimination of causative microorganisms. The clinical effects were classified into 4 grades;Complete response,significant response,progress and no response. Microbial sensitivity to isepamicin was tested by using MH culture medium and KB method. RESULTS :The total response rate was 88% and bacteria clearance rate 80%. The flatulence and pain at injected site were occurred in one patient. BUN increased slightly in 2 patients. CONCLUSION :Isepamicin is an effective drug in the treatment of UTI.Adverse reactions are mild.
出处
《新药与临床》
CSCD
北大核心
1996年第5期297-298,共2页
关键词
异帕米星
氨基糖苷类
尿路感染
药物疗法
isepamicin
aminoglycoside
urinary tract infection
microbial sensitivity tests