Ⅳ期肺癌双介入治疗的探讨

Study of Double Interventional Treatment(DIT) on Pulmonary Carcinoma Type PT4

目的:探讨不同类型Ⅳ期肺癌(PT4)介入治疗的方法及其疗效。材料和方法:45例PT4中并肺内转移者15例,采用支气管动脉与肺动脉同时灌注化疗;并全肺叶不张者15例,采用支气管动脉与胸主动脉同时灌注化疗;并同侧胸积液者15例,采用支气管动脉加胸膜腔内灌注的双介入方法。结果:完全缓解7例,占15.6％;部分缓解13例,占28.9％;无变化20例,占44.4％;有进展5例,占11.1％。结论:双介入治疗PT_4的临床疗效与全身化疗相持平,甚至在某些方面优于全身化疗,这就为Ⅳ期肺癌的治疗另辟了一条途径并提供了科学依据。

Purpose: To discuss the methods and the effects of DIT on pulmonary carcinoma Type PT4 Materials and methods: This Procedure was performed in 45 cases with Pulmonary Carcinoma Type PT4 using infusion of chemotherapeutical agent through catheterized bronchial and pulmonary arteries, bronchial artery and thoracic aorta or bronchial artery and intrapleural cavity respectevely on central pulmonary carcinomas complicating with metastasis in lung 15 cases, complete atelectasis 15 cases or ipsilateral hydrothorax 15 cases. Results: 7 cases were complete relaxed (CR15.6%); 13 partial relax ed (PR28.9%); 20 nochange (44. 4% ); 5 enlarged (11.1% ). Conclusion: The results showed this method is some what egnal to or ever in some aspects, prevalent over that of systematic chemotherapy theretore provides new scientific method for thel treatment of pulmonary carcinoma Type PT4.