肺癌组织红外光谱的统计分析

The FTIR Spectroscopic Statistics Analysis on Tissues of Lung Cancer

使用统计的方法,应用傅里叶变换红外光谱法对肺癌及癌旁正常组织粉末样品的红外光谱进行了统计分析。结果表明,肺癌组织和癌旁正常组织的红外光谱有显著的差异性:3306cm-1处的N-H峰在肺癌组织中向低频移动了约3cm-1;1167cm-1处的C-OH伸缩振动谱带在肺癌组织中向高波数移动约6cm-1;1080cm-1处的PO2-对称伸缩振动谱带在肺癌组织中向高波数移动约4cm-1。体现了在肺癌组织中细胞形态和组织结构发生的变化,说明傅里叶变换红外光谱法可以用于对良、恶性肺部组织鉴别诊断。

Using statistics method, Fourier transform infrared （FTIR） spectroscopy was applied to the study of the spectrum of the powder of cancerous tissues and normal tissues near the cancer of the lung. The results showed that there were significant differences in the FTIR spectra between the normal and malignant pulmonic tissues： the peak at 3306cm^-1 of N-H shifted 3cm^-1 to short wavenumber in cancerous tissues, the peak at 1167cm^-1 of C-OH shifted 6 cm^-1 to long wavenumber in cancerous tissues, the peak at 1080 cm^-1 of PO2^- shifted 4 cm^-1 to long wavenumber in cancerous tissues. These difference embodies the variety of cell＇s structure and shape, this might indicate the FTIR could be a new method of the clinical diagnoses of the lung cancer.