摘要
随着新药的不断开发应用及各种药物的联合应用增多,药物性肝损伤的发生率不断增加,引起人们对药物性肝损伤的重视及研究,目前在遗传学、蛋白质组学等方面取得较大进展。现就引起肝损伤的药物、发病机制、临床分类及其表现、易感因素等加以综述。
With the increase of development and application of new drugs and combined application of many varieties of drugs, the incidence rate of drug-induced liver injury has increased gradually,and this has caused our attention and study. Now it has made great advancement in genetics, proteomics etc. We will review the drugs, pathogenesis, clinical classification and appearance, susceptible factors induced liver injury in this article.
出处
《国际消化病杂志》
CAS
2007年第1期21-24,共4页
International Journal of Digestive Diseases
关键词
肝损伤
药物性
发病机制
临床分类
易感因素
预后指标
Liver injury
Drug-induced
Pathogenesis
Clinical classification
Susceptible factors
Prognostic indicator