摘要
自上世纪九十年代以来,免疫调节剂已成为炎症性肠病(IBD)系统治疗的重要组成部分,尤以硫唑嘌呤(AZA)、6-巯基嘌呤(6-MP)、环孢素A(CsA)、甲氨蝶呤(MTX)应用最广泛。使用免疫调节剂可能出现强烈而明显的不良反应,用药时应仔细监测。此文主要就AZA、6-MP、CsA、MTX治疗炎症性肠病的监测及不良反应作一综述。
Treatment of inflammatory bowel disease（IBD） commonly requires utilization of immunodulatory medications. The most commonly immunomodulators used for treatment of IBD are azathioprine, 6-mercaptopurine, cyclosporine and methotrexate. Great care must be taken in monitoring patients who receive these medications to reduce the risk of side-effects and toxicity. This review will provide information on monitoring of metabolites and the adverse reactions profile for each medication.
出处
《国际消化病杂志》
CAS
2007年第1期41-44,共4页
International Journal of Digestive Diseases
关键词
炎症性肠病
免疫调节剂
监测
不良反应
Inflammatory bowel disease
Immunomodulator
Monitoring
Adverse reactions
