维持性血液透析患者眼底观察

Observation of eyeround changes in patients before and aftor hemodialysis

目的:了解血液透析患者透析前后眼底改变情况,探讨影响血液透析眼底改变的因素。方法:分别于血液透析开始和透析12个月时观察血压、血红蛋白、尿素氮、血肌酐以及眼底改变。结果:透析一年后眼底改变的发生率为65.6%,低于透析前眼底改变的发生率84.4%,但无显著性差异(P>0.05);视网膜出血、渗出和水肿3项改变的发生率透析后较透析前明显下降(P<0.01);视网膜动脉硬化血透后较血透前升高,但无显著性差异(P>0.05)。结论:维持性血透患者透析前和透析后眼底改变的发生率较高,与尿毒素升高、高血压、贫血、水肿等有关,且眼底改变在一定程度上反映了患者全身情况和预后的好坏。

Objective：To observe the eyeground changes of the patients before and after hemodialysis and investigate influential factors of eyeground change.Methods：Blood pressare, hemoglobin,BUN,Scr were detected at the beginning and 1 year of hemodialysis.Results：Incidence rate of eyeground change after 1 year was 65.6%,it was lower than that of before hemodialysis （84.4%）.Though no statistical difference （P〉0.05）,the incidence rate of retinal hemorrhage,exudation and edema was lower significantly than that of before hemodilysis（P〈0.01）.Conclusion：The incidence rate of eyeground change before and after maintenance hemodialysis both increase,eyeground changes are related to anemia hypertensive edema et al and reflect the condition and prognosis of patients in some extent.