侵袭性脑膜瘤的临床特点及外科治疗

Clinical Characteristics and Surgical Treatment of Invasive Meningiomas

目的探讨侵袭性脑膜瘤的临床、病理特征及外科治疗。方法回顾性分析了69例经手术证实的侵袭性脑膜瘤患者的临床表现、病理及术前影像学特点及术中所见。结果69例中,首发症状表现为颅内压增高32例,颅神经功能障碍17例,癫痫11例,其他9例。病理为WHOⅠ级56例,Ⅱ级6例,Ⅲ级7例。手术切除SimpsonⅠ级34例,Ⅱ级28例,Ⅲ级及以上7例。结论侵袭性脑膜瘤组织病理学分类以WHOⅠ级最多见,术前影像学表现有助于手术方案的制定,对其应进行以手术全切肿瘤及受侵犯硬膜为主的综合治疗。

Objective To analyze the clinical and pathological characteristics of the invasive meningioma and its surgical treatment. Method The clinical data of 69 patients with invasive meningiomas, including the clinical manifestataions, pathological examination, preoperative imagings and intraoperatively observed somethings, were analyzed retrospectively. Results The symptoms included increase in the intracranial pressure in 32 patients, the functional disturbance of cranial nerves in 17, epileptic seizure in 11 and other symptoms in 9. According to WHO standard of pathological classification , 56 belonged in grade Ⅰ, 6 in grade H and 7 in grade Ⅲ. According to Simpson standard of resecting tumor, grade Ⅰ was reached in 34 cases, grade Ⅱ in 28 and grade Ⅲ or more in 7. Conclusions Most of the invasive meningiomas were benign. The preoperative imaging is helpful to making operative plan. Surgery is the basic treatment of invasive meningioma.