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突触体素在甲状腺功能减退大鼠脑海马发育期的表达 被引量:7

Expression of synaptophysin in the developmental hippocampus of hypothyroid rats
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摘要 探讨甲状腺激素对发育关键期大鼠海马各区突触体素表达的作用和影响,结果提示在脑发育关键期,甲状腺激素水平的减少改变了海马各区突触体素mRNA的表达和时相性,进而影响了该区域突触的发生及相关神经回路的建立。 The effects of thyroid hormone on the synaptophysin (syn) expression were studied in the developmental period of rat hippocampus. The results suggest that the thyroid hormone reduction leads to the change of syn mRNA expression in the rat hippocampus and further affects development of synapse and establishment of related nerve circuit there.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2007年第1期72-74,共3页 Chinese Journal of Endocrinology and Metabolism
关键词 甲状腺激素类 甲状腺功能减退症 突触 海马 突触体素 Thyroid hormones Hypothyroidism Synapses Hippocampus Synaptophysin
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  • 1闫玉芹,王丹娜,张宏明,李晓哲,邢雅珊,原弘,山根敏子,宫崎惠利子.NF、MBP、Synaptophysin、GFAP在地方性克汀病人和缺碘及甲低大鼠小脑中的分布[J].中国地方病防治,1996,11(2):68-71. 被引量:5
  • 2Daly C, Sugimori M, Moreira JE. Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles [ J ]. Proc Natl Acad, 2000,97(11) :6120-6125.
  • 3Daly C, Ziff EB. Ca^2+ -denpendent for nation of a dynamin-synaptophysin complex:potential role in synaptic vesicle endocytosis[ J]. J Biol Chem,2002,277( 1 ) :9010-9015.
  • 4Tarsa L, Goda Y. Synaptophysin regulates activity-dependent synase formation in cultured hippocampal neurons [ J ]. Proc Natl Acad Sci USA.2002,99(2) : 1012-1016.
  • 5MuUany PM, Lynch MA. Evidence for a role for synatophysin in expression of long-term Potentiation in rat dentate gyrus [ J ]. Neuroreport,1998,9( 1 ) : 2489.
  • 6Morys J, Berdel B, Kowinski P, et al. The pattern of synaptophysin changes during the maturation of the amygdaloid body and hippocampal hilus in the rat [ J ]. Folia Neuroathol, 1998,36 ( 1 ) : 15.
  • 7Rao H, Pio J, Kessler JP. Postnatal development of synaptophysin immunoreactivity in the rat nucleus tractus solitarii and caudal ventrolateral medlla[J] .Brain Res Dev Brain Res,1999,112(2):281-285.
  • 8Sarnat HB, Born DE. Synaptophysin immunocytochemistry with thermal intensification : a marker of terminal axonal maturation in the human fetal nervous system[J] .Brain Dev,1999,21(1) :41-50.
  • 9Stroemer RP, Kent TA, Hulsebosch CE, et al. Neocortical neural sprouting synaplogenesis and behavioral recovery after neocortical infarction in mts[J]. Stroke, 1995,26( 11 ) :2L35-2144.
  • 10Ishimaru H, Casamenfi F, Veda K, et al. Changes in presynaptic SNAP-25 and synaptophysin,in the hippocampal CA1 area in ischemic gerbils[J] .Brain Res,2001,903(1-2) :94-101.

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