早期减压并应用大剂量甲基强的松龙治疗急性脊髓损伤

Early Decompression and High—dose Methylprednisolone Treatment in Acute Spinal Cord Injury

目的:观察与分析早期手术减压并大剂量应用甲基强的松龙(methylprednisolone MP)治疗急性脊髓损伤(acute spinal cord mjury ASCD的疗效。方法:收录我科1999年月7月～2005年3月急性脊髓损伤的76例患者,根据治疗方法的不同分为手术减压组32例,单独应用甲基强的松龙处理组18例和早期减压并同时应用大剂量MP联合治疗组26例,比较神经功能恢复情况。结果:早期手术减压和大剂量应用MP对ASCI治疗都是有效的,联合早期减压和应用大剂量MP可以提高ASCI患者的神经功能恢复。结论:早期手术减压并大剂量应用MP对促进脊髓功能恢复具有积极的意义。

Objective：Observing and analyzing the effects of early decompression and high-dose methylprednisolone in treatment of acute spinal cord injury（ASCI）. Methods： 76 cases with ASCI were divided 3 groups by different treatments, Operation group （32 cases） , MP group（ 18 cases） and united group（26 cases）, Compared the JOA scores of different groups. Resuits：Early decompression or high-dose methylprednisolone was effect in treatment of ASCI, and united early decompression and high --dose methylprednisolone can improve the neuro-function of patients with ASCI. Conclusion： Early decompression and high-dose methylprednisolone were positive effects for neuro-function, and we suggested use them to treat patients with ASCI.