蒙药胃舒安胶囊的质量标准研究

Study on Quality Standard for Mongolin Medicine Weishu′an Capsule

目的:建立蒙药胃舒安胶囊的质量标准。方法:采用薄层色谱法对制剂中的大黄、栀子、荜茇等3味药进行定性鉴别;HPLC对制剂中的大黄有效成分大黄素和大黄酚进行定量分析。结果:大黄素平均回收率97.22%,RSD=0.33%;大黄酚平均回收率97.53%,RSD=0.77%(n=5)。结论:该方法操作简便、可行、重现性好、结果满意能准确监控该制剂的质量。

Objective： To establish the methods for controling quality of mongolin medicine weishu＇an capsule. Methods： Radix et rhizome rhei, Fructus gardeniae and Fructus piperis longi from its preparation were identifined by TLC and the main active compositions in Radix et rhizome rhei like chrysophanol and emodin from the preparation were determined by HPLC. Results： The average recovery is 97.22%, RSD =0. 33% on emodin, and 97.53%, RSD = 0. 77 % on chrysophanol （ n = 5 ） Conclusion.. The methods are simple, feasible, goodre - appearance, and can control the quality of the preparation accurately.