期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

肝切除及肝移植术中缺血预处理的临床研究进展 被引量：3

Advance of ischemic preconditionting in hepatectomy and liver transplantation
原文传递
导出
摘要 缺血再灌注损伤一直是肝切除及肝移植术中存在的问题，是术后肝功能衰竭和移植物无功能的主要原因，而缺血预处理能减轻这种损伤。文中综述了近年来缺血预处理及其在临床应用中的研究进展，探讨了该技术在临床上的实用价值。 Ischemic reperfusion injury（IRI） always residing in hepatectomy and liver transplantation, is the most important factor of oiver dysfunction and non-function of allografi after hepatic surgery, and ischemic preconditioning （IP）can reduce this injury. The article reviewed the literatures on basic researcl and clinical application of IP in recent years, and studied its clinical value.
作者 侯辉 耿小平
机构地区 安徽医科大学第一附属医院肝胆外科
出处 《国际外科学杂志》 2007年第2期128-131,共4页 International Journal of Surgery
关键词 缺血再灌注损伤 缺血预处理 肝切除术 肝移植术 ischemic reperfusion injury ischemic preconditioning hepatectomy liver transplantation
分类号 R657 [医药卫生—外科学]
  • 相关文献

参考文献24

  • 1Murray CE,Jenning RB,Reimer KA.Preconditioning with ischemia:a delay in lethal cell injury in ischemic myocardium[J].Circulation,1986,74(5):1124-1136.
  • 2Schauer RJ,Gerbes AL,Vonier D,et al.Induction of cellular resistance against Kupffer cell-derived oxidant stress:a novel concept of hepatoprotection by ischemic preconditioning[J].Hepatology,2003,37(2):286-295.
  • 3Uchinami H,Yamamoto Y,Kume M,et al.Effect of heat shock preconditioning on NF-kappa B/I-kappa B pathway during I/R injury of the rat liver[J].Am J Physiol Gastrointest liver Physiol,2002,282(6):962-971.
  • 4Kobayashi A,Imamura H,Isobe M,et al.Mac-1(CD11b/CD18) and intercellular adhesion molecule-1 in ischemia-reperfusion injury of rat liver[J].Am J Physiol Gastrointest Liver Physion,2001,281(2):577-585.
  • 5Scommotau S,Uhlmann D,Loffler BM,et al.Involvement of endothelin/nitric oxide balance in hepatic ischemia/reperfusion ijury[J].Langenbecks Arch Surg,1999,384(1):65-70.
  • 6Arai M,Thurman RG,Lemasters JJ.Contribution of adenosine A(2) receptors and cyclic adenosine monophosphate to protective ischemic preconditioning of sinusoidal endothelial cells against storage/reperfusion injury in rat livers[J].Hepatology,2000,32(2):297-302.
  • 7Sasaki H,Matsuno T,Tanaka N,et al.Activation of apoptosis during the reperfusion hpase after rat liver ischemia[J].Transplant Proc,1996,28(3):1908-1901.
  • 8Jaeschke H,Lemasters JJ.Apootosis versus oncotic necrosis in hepatic ischemia/reperfusion injury[J].Gastroenterology,2003,125(4):1246-1257.
  • 9Carini R,De Cesaris MG,Splendore R,et al.Signal pathway involved in the development of hypoxic preconditioning in rat hepatocytes[J].Hepatology,2001,33(1):131-139.
  • 10Harada N,Hatano E,Koizumi N,et al.Akt activation protects rat liver from ischemia/reperfusion injury[J].J Surg Res,2004,121(2):159-170.

同被引文献25

  • 1Shao-QiangLi,Li-JianLiang,Jie-FuHuang,ZhiLi.Ischemic preconditioning protects liver from hepatectomy under hepatic inflow occlusion for hepatocellular carcinoma patients with cirrhosis[J].World Journal of Gastroenterology,2004,10(17):2580-2584. 被引量：20
  • 2李晓芳,范昕建,王文雅.人工肝临床应用的研究进展[J].西部医学,2005,17(1):70-72. 被引量：1
  • 3区金锐,陈伟,简志祥,郑江华.不同肝血流阻断方式在肝癌手术中应用的对比研究[J].中华普通外科杂志,2005,20(1):43-44. 被引量：14
  • 4Yokoyama T, Ohashi K, Kuge H, et al. In vivo engineering of metabolically active hepatic tissues in a neovascularized subcutaneous cavity [J]. Am J Transplant, 2006; 6(1) :50
  • 5Terry C, Dhawan A, Mitry RR, et al. Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing [J]. Liver Transpl, 2006; 12(1): 165
  • 6Jamal HZ, Weglarz TC, Sandgren EP. Cryopreserved mouse hepatocytes retain regenerative capacity in vivo [J]. Gastroenterology, 2000; 118(2) : 390
  • 7Aleem Khan A, Parveen N, Habeeb MA, et al. Journey from hepatocyte transplantation to hepatic stem cells: a novel treatment strategy for liver diseases [J]. Indian J Med Res, 2006; 123(5) : 601
  • 8Rahman TM, Diakanov I, Selden C, et al. Co-transplantation of encapsulated HepG2 and rat Sertoli cells improves outcome in a thioacetamide induced rat model of acute hepatic failure [J]. Transpl Int, 2005; 18(8) : 1001
  • 9Dagher I, Boudechiche L, Branger J, et al. Efficient hepatocyte engraftment in a nonhuman primate model after partial portal vein embolization [J]. Transplantation, 2006; 82(8) : 1067
  • 10Bilir BM, Guinette D, Karrer F, et al. Hepatocyte transplantation in acute liver failure [J]. Liver Transpl, 2000; 6(1): 32

引证文献3

二级引证文献3

国际外科学杂志
2007年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部