兰山区2003～2005年健康人群麻疹抗体水平监测分析

Suveillance of measles antibody level of health population of Lanshan in 2003～2005

目的了解兰山区2003～2005年健康人群麻疹抗体水平，为加速控制和消除麻疹提供科学依据。方法随机抽样调查，采用酶联免疫吸附试验（EHSA）间接法测定特异性麻疹IgG抗体。结果调查409人，麻疹IgG抗体阳性393人，阳性率96．09％。几何平均滴度（GMT）为1：1530。不同年龄组抗体水平有显著性差异，抗体水平随着年龄增加呈现下降的趋势。结论兰山区人群麻疹抗体水平较高，基本形成了预防麻疹的免疫屏障，对控制麻疹的发病起到了积极的作用，应对重点人群实行麻疹疫苗加强免疫。

Object To understand measles virus specific Ig antybody level in 2003 ～ 2005 and offer scientitle basis for confrolling measles. Methods We chose population of Lanshan district as the subjects. The measles virus specific IgG antybody was detected by the enzyme - linked innunosorbent assay. Results The total subjects were 409, and the positive rate of IgG was 96.09% ,the GMT was 1 ： 15300 The seropositive rate and the GMT level were all significant difference in different age groups, it had a trend that the antybody decreased followed by the age increase. Conclusion There was high measles antybody level in health population of Lanshan district and it exert a oositive effect to prevent measles.