氧氯化铜的毒性研究

Toxicity study on copperoxychloride.

氧氯化铜急性经口ＬＤ＿（５０）在雄性大鼠为２７５６ｍｇ／ｋｇ，雌性大鼠为４３１７ｍｇ／ｋｇ，雌雄有显著性差异；小鼠的急性经口ＬＤ＿（５０）为１１３０ｍｇ／ｋｇ，雌雄无显著性差异。Ａｍｅｓ试验、小鼠骨髓细胞微核试验和小鼠精子畸形试验均未发现其诱变性；氧氯化铜对皮肤无刺激性。结果表明氧氯化铜属低毒类农药，其使用是较为安全的。

he acute oral LD50 of copper oxychloride in ratswas shown to be 2756mg/kg in male and 4317mg/kgin female respectively, indicating a sexal difference.The acute oral LD50 in mice was 1130mg/kg. No sexaldifference was observed. No Ynutagenicity was shownby Ames test, micronucleus test of bone marrow celland sperm shape abnormality test in mice. Skin irrita-tion was not found in rabbits. The results demon-strates that copper oxychloride may be classified aslow toxicity pesticide and that its application is rela-tively safe.