低水平铅接触对男工性机能及生殖结局的影响

Effect of low level lead exposure on sexual function and reproduction outcome of workmen

本文研究了接触低水平铅男工的性机能和生殖结局状况。接铅组性机能障碍发生率为１１．８０％，对照组为４．４８％，两组比较差异非常显著（Ｐ＜０．０１），早泄（１１．８０％）、性欲减退或无性兴奋性（１４．６％）的发生率也显著高于对照组（４．９３％、４．０４％）。性机能障碍和早泄发生率有随工龄增加而增高的趋势（Ｐ＜０．０５、Ｐ＜０．０１）。接铅男工妻子的自然流产率（９．５０％）、死胎死产率（２．２３％）和不育率（８．４３％）也分别高于对照组（５．５２％、０．４８％、２．６９％）。自然流产率的增高主要表现为早期自然流产率的增高，发生率与对照组比较有极显著差异（Ｐ＜０．０１）。Ｌｏｇｉｓｔｉｃ回归分析显示，铅接触是自然流产率、死胎死产率和不育率增高的唯一危险因素（Ｐ＜０．０１）。

A study of sexual function of male printing wor kers was carried out Only low level lead exposure resulted in sexual dysfunction and abnormal reproduction outcome The incidence of sexual disorder in the lead exposed workmen was 11 80% and significantly higher than that of the control group( P <0 01) The incidence of premature ejaculation(11 8%), sexual hypoasthenia and no sexual desire(14 61%) were also significantly higher than those of the control group( P <0 05, P <0 01) Stratified study of working year showed that the incidence of sexual dysfunction and premature ejaculation were increased along with the working year The risk of spontaneous abortion, stillbirth, dead fetus and infertilith of the lead exposed workmens wife increased about 1 72,4 6 and 3 1 folds greater and significantly highter than those of control group The increase of spontaneous abortion was mainly prevalent in the early period of pregnancy, and significantly higher than that of the control group The result of logistic regression analysis showed that lead exposure would be the only risk factor which might increase the incidence of spontaneous abortion, dead fetus, stillbirth and infertility