吸烟与细菌性阴道病关系的研究

Study on Relationship Between Cigarette Smoking and Bacterial Vaginosis

目的:探讨吸烟与细菌性阴道病(BV)的关系。方法:对某医院妇产科门诊接受计划生育服务的育龄妇女非选择性地进行BV筛检。以筛检出的BV患者267例为病例组,其余478例未患BV且无BV史的妇女为对照组进行病例对照研究。结果:BV患者中吸烟者占8.99%(24/267),对照组中吸烟者占2.93%(14/478)。单因素非条件Logistic回归分析显示,吸烟与BV有统计学关联(OR=3.273,95%CI:1.663～6.442,P=0.001);经婚姻状况、性卫生、性行为习惯调整后,吸烟与BV之间的正关联仍有统计学意义(OR=3.425,95%CI:1.660～7.066)。结论:吸烟可以增加BV发生的危险,吸烟是BV独立的危险因素。控烟是预防BV发生的重要措施。

Objective： To investigate if there is an association between cigarette smoking and bacterial vaginosis （BV） Methods： An unselected screening for BV was conducted among women at childbearing age accepting family planning services at two hospitals in Chengde city. A case - control study was conducted based on it. In which 267 patients with BV, 478 women without BV and＇BV history as controls were interviewed. Results： Of the women with BV, 9. 0% were smokers versus 2. 9% in the control group. Univariate non - conditional logistic regression model analysis showed that cigarette smoking was Significantly associated with BV. Odds ratio （OR） for smokers was 3.273 （95% confidence interval （CI） 1.663 -6.442, P=0.001） . After adjustment for marital status , sexual sanitation and behaviors, the positive association between cigarette smoking and BV was still significantly, OR = 3. 425 （95% CI： 1. 660 - 7. 066） . Conclusion： Smokers are liable to bacterial vaginosis, and cigarette smoking is an independent risk factor of BV. Smoking control might have some preventive impact on the incidence of BV.