摘要
转化生长因子-β是一类多功能细胞因子,在体内分布广泛,在不同器官的细胞中有着不同的生物学效应,其涉及到胚胎发生、器官发育、组织修复以及机体免疫等调节过程,该细胞因子已经成为衰老研究的一个靶点。本文就转化生长因子β基因的生物学特性、生物学功能、基因多态性及其与衰老的联系作一简要的综述。
Transforming growth facctor-β is a Guangixi multifunctional eytokine with widespread distribution in body. Its biological effects are different according to different tissue, which includes the regulation of embryogeny, allelotaxy, tissue repair and body imnrme. Transforming growth factor-beta-β has been the study target of human aging. This article reviews Tranffonning growth factor-beta-β about its bionomics, biological function, gene polymorphism, and its relationship with aging.
出处
《医学综述》
2007年第6期403-405,共3页
Medical Recapitulate
基金
广西科学基金(桂科青0542044
桂科自0339041)
