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抗嗜中性粒细胞胞质抗体相关性系统性血管炎免疫学研究进展 被引量：1

Immunologic Study Progress of ANCA Associated Systemic Small Vasculitis
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摘要 抗嗜中性粒细胞胞质抗体相关性系统性血管炎(AASV)是近年来渐受关注的一类由遗传、环境及免疫等诸多因素共同作用所致的公认的系统性自身免疫性疾病。其发病机制较为复杂,本文从ANCA、内皮细胞及其抗体、细胞因子、T细胞和免疫复合物五方面对其免疫学的研究进展进行简要综述。 Antineutrophil cytoplasmic autoantibodies（ANCA） associated systemic vaseulitis（AASV） is a systemic autoimmune disease resulting from muhiple factors such as inheritance,environment and immunity etc, which is attracting more attention recently, The pathogenesy of AASV is fairly complex, this text will summarize the progress of Immunologic study of AASV from five aspects including ANCA,endothelial cell and its antibody,eytokine,T horneoeyte and immunoeomplex.
作者 项新 廖蕴华
机构地区 广西医科大学第一附属医院肾内科
出处 《医学综述》 2007年第6期408-410,共3页 Medical Recapitulate
关键词 ANCA 小血管炎 免疫学 ANCA Polyangitis Immunology
分类号 R543 [医药卫生—心血管疾病]
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参考文献17

  • 1Xiao H,Heeringa P,Hu P.Antinentrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice[J].J Clin Invest,2002,110(7):955-963.
  • 2Hattar K,Bickenbach A,Csernok E,et al.Wegener's granulomatosis:Antiproteinase 3 antibodies induce monocyte cytokine and prostanoid release role of autocrine cell activation[J].J Leukoc Biol,2002,71(6):996-1004.
  • 3Csernok E.Anti-neutrophil cytoplasmic antibodies and pathogenesis of small vessel vasculitides[J].Autoimmue Rev,2003,2(3):158-164.
  • 4Savage CO,Harper L,Holland M.New findings in pathogenesis of antineutrophil cytoplasm antibedy-associated vasculitis[J].Curr Opin Rheumatol,2002,14(1):15-22.
  • 5Yang JJ,Preston GA,Alcorta DA,et al.Expression profile of leukocyte genes activated by anti-neutrophil cytoplasmic autoantibedies(ANCA)[J].Kidney Int,2002,62(5):1638-1649.
  • 6PraprotniK S,Rozman B,Blank M,et al.Pathogenic role of anti-endo-thelial cell antibodies in systemic vasculitis[J].Wien Klin Wochenschr,2000,112(15-16):660-664.
  • 7Lee KH,Cho HJ,Kim HS,et al.Activation of extracellular signal regulated kinase 1/2 in human dermal microvascular endothelial cells stimulated by anti-endothelial cell antibodies in sera of patients with Behcet's diseas[J].J Dermatol Sci,2002,30(1):63-72.
  • 8Bordron A,Dueymes M,Levy Y,et al.the binding of some human anti-endothelial cell antibodies induces endothelial cell apoptosis[J].J Clin Invest,1998,101(10):2029-2035.
  • 9Zhou Y,Giscombe R,Huang D,et al.Novel genetic association of Wegener's granulomatosis with the interleukin 10 gene[J].J Rheumatol,2000,29(2):317-320.
  • 10Schonermarck U,Csemok E,Trabandt A,et al.Circulating cytokines and soluble CD23,CD26 and CD30 in ANCA-associated vasculitied[J].Clin Exp Rheumatol,2000,18(4):457-463.

同被引文献32

  • 1李东升,王玮蓁,孙春艳,戴明,朱林学,段逸群.系统性红斑狼疮患者B淋巴细胞刺激因子及其受体BAFF-R的表达[J].中华皮肤科杂志,2006,39(1):10-12. 被引量：13
  • 2李晓琳,侯宗柳（审校）.BAFF信号的免疫调节作用[J].国际免疫学杂志,2006,29(6):368-372. 被引量：5
  • 3Borregaard N, Sorensen OE, Theilgaard-Monch K. Neutrophil granules : a library of innate immunity proteins [ J ]. Trends Im- munol, 2007, 28 ( 8 ) :340-345.
  • 4Kumar V, Sharma A. Neutrophils: Cinderella of innate inmmne system[ J ]. Int Immunopharmacol,2010,10 ( 11 ) : 1325-1334.
  • 5Lincoln JA, Letkowitz DL, Cain T,et al. Exogenous myeloperoxi- dase enhances bacterial phagocytosis and intracellular killing by macrophages [ J ]. Infect Immun, 1995,63 ( 8 ) :3042-3047.
  • 6Bennouna S, Bliss SK, Curiel TJ,et al. Cross-talk in the innate immune system: Neutrophils instruct recruitment and activation of dendritic cells during microbial infection[ J]. J Immunol, 2003, 171 ( 11 ) :6052-6058.
  • 7Ethuin F, Gerard B, Benna JE,et al. Human neutrophils produce interferon gamma upon stimulation by interleukin-12 [ J]. Lab In- vest, 2004, 84(10) :1363-1371.
  • 8Scapini P, Carletto A, Nardelli B, et al. Proinflammatory media- tors elicit secretion of the intracellular B-lymphocyte stimulator pool( BLyS )that is stored in activated neutrophils: implications for inflammatory diseases [ J ]. Blood, 2005, 105 (2) :830-837.
  • 9Urban CF, Ermert D, Schmid M,et al. Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against candida albicans[ J]. PLoS Pathog, 2009,5 (10) :1371.
  • 10Ramos-Kichik V, Mondragon-Flores R, Mondragon-Castelan M, et al. Neutrophil extracellular traps are induced by Mycobacteri- um tuberculosis [ J ]. Tuberculosis (Edinb) , 2009, 89 ( 1 ) : 29-37.

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医学综述
2007年 第6期

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