摘要
先天性心脏病(简称先心病)合并肺动脉高压是严重影响我国儿童身心健康的主要疾病之一,其复杂的发病机制仍未完全明了。但是,近年来对于先心病病理生理条件的动物模型的建立、肺组织的病理学资料与血液分子水平的生化指标的研究日益增多,并已取得较大进展。本文综述了近几年来国内外有关先心病、PH发病机制的研究进展,以便能更深入理解其机制,指导临床治疗。
Congenital heart disease （CHD）with pulmonary hypertension is one of the most serious diseases that influence the children＇s health in both body and mind in our country,whose complex pathogenic mechanism is not completely clear now. The increasing study of the establishment of animal model with congenital heart disease , pathologic data of lung tissue and blood biochemical indicator in molecular level has achieved a great progress. This article reviews research progress of internal and abroad congenital heart disease and pathogenesis of PH in order to understant its mechanism further and then instruct clinical therapy.
出处
《医学综述》
2007年第6期453-455,共3页
Medical Recapitulate
关键词
先天性心脏病
肺动脉高压
发病机制
Congenital heart disease
Pulmonary hypertension
Pathogenic mechanism
