9125例泌尿生殖道感染者支原体检测及药敏分析

Detection of Mycoplasma Infection in Genitourinary Tract of 9125 Patients and Results of Drug Sensitive

目的:了解泌尿生殖道感染者支原体感染率及耐药情况,指导临床合理用药。方法:采用支原体分离、鉴定、药敏一体化检测板培养法对9125例患者进行解脲、人型支原体检测及药敏分析。结果:支原体培养阳性4 766例(52.23%),单纯Uu感染4723例(51.76%),Mh、Uu合并感染38例(0.40%),单纯Mh感染5例(0.05%)。对交沙霉素(99.40%)、强力霉素(94.80%)最为敏感,其次为美满霉素(93.20%)和克拉霉素(91.30%),对左旋氧氟、司帕沙星、四环素、氧氟沙星等敏感性差,敏感率分别为79.30%、72.60%、63.70%和61.70%。结论:支原体对常用抗生素有不同程度的耐药性,不同类型支原体感染表现的耐药性不一致,Mh、Uu合并感染比单纯Uu感染有较高耐药性,因此,临床诊治前应尽可能做支原体培养及药敏试验,合理、规范用药。

Objective： To explore the infectious rate and drug resistance of mycoplasma from patients with genitourinary tract infection in Xiamen. Methods：Mycoplasma IST Cultural Kit with the function of incubation and identification,colonial counting and drug sensitivity from 9 125 patients with genitourinary tract infection. Results： Out of 9 125 patients, there were 4 766 cases with mycoplasma,the positive was 52.23%. Among them,4 723 cases were simple UU infection （51.76%） ;38 cases were mixed infection of UU plus MH（0.40%） ;5 cases were MH simple infection（0. 05%）. The highest sensitive drugs were josamycin （99. 40%）and deoxycyline （94.80%） ,minoccyline （93.20%）and clarithromycin （91.30%） being the second. The sensitivenesses of levofloxacin, sparfloxacin, tetracycline, ofloxacin, etc. were bad, and the rates were 79.30%,72.60%, 63.70% and 61.70%, respectively. Conclusion： Mycoplasma has the varying susceptibility to the commonly antibiotic. The different kinds of mycoplasma infection performance susceptibility is inconsistent. Mixed infection of MH and UU is higher susceptibility than that of the simple UU infection. Therefore, before the clinical diagnosis should do the mycoplasma cultivation and the drug sensitivity test as far as possible, it is reasonable and standard medication.