急性脑梗死的^1HMRS波谱分析

The Analysis of 1HMRS in the Patients with Acute Cerebral Infraction

目的：分析急性脑梗死的氢质子磁共振波谱成像（^1Hnuclear magnetic resonance spectroscopy，^1HMRS）的成像特征，评价-HMRS对急性脑梗死的诊断价值。方法：17例急性脑梗死患者均行常规MRI（T1FLAIR（fluid affenuated inversion recovery，FLAIR）、T2WI、T2FLAIR）扫描及弥散加权成像（diffusion weighted imaging，DWI）和。HMRS扫描。多体素点分辨波谱（point resolved spectroscopy sequence，PRESS），TE144ms定域序列采集灶中心，比较分析代谢物出现概率。1～2个月后行常规MRI检查。结果：17例患者在1．05ppm处均出现倒置乳酸（Lac）峰，15例梗死区NAA峰不同程度降低，半暗带NAA峰正常。结论：磁共振。HMRS波谱分析与DWI相结合，可实现对急性脑梗死较为全面的评估。

Objective： To retrospectively analyze the ^1HMRS features of acute cerebral infraction, and to evaluate its value in the diagnosis. Methods： Seventeen patients with acute cerebral infraction underwent routine MRI（including T1FLAIR FSE-T2WI FLAIR and DWI） and ^1HMRS. Multiple-voxel PRESS（144ms） sequence was performed and metabolite were analyzed. Follow-up routine MR was performed 1 to 2 months after the first MRI examination. Results： All 17 cases showed inversion lac in the 1.05 ppm,15 did NAA decreased in different degree,9 did high Glx, 13 did normal NAA in the half-hidden area. Conclusion： By combination of 1HMRS and DWI , full-scale evaluation of acute cerebral infraction can be achieved.