IIEF-5在血管性勃起功能障碍诊断中的应用

IIEF-5 Cannot Be Used as a Tool for Differential Diagnosis of Vasculogenic Erectile Dysfunction

目的:评价国际勃起功能简化量表(IIEF-5)对血管性勃起功能障碍(ED)病因区分的意义,以指导血管性ED诊断及治疗。方法:将103例ED患者分为4组,非血管性ED组37例(37/103,35.9%)、动脉性ED组18例(18/103,17.5%)、静脉性ED组35例(35/103,34.0%)、混合性ED组13例(13/103,12.6%),其IIEF-5得分与海绵体血管活性药物注射试验结果、多普勒超声检查结果及双核素检测结果进行比较,以非参数检验的多个独立样本检验(Kruskal-WallisTEST)比较各组之间IIEF-5得分差异的显著性。结果:上述4组之间的IIEF-5得分没有统计学差异(P=0.253)。结论:IIEF-5不能作为一种诊断工具用于鉴别血管性ED的病因以及判断血管病变严重程度。

Objective： To evaluate the 5-item version of the international index of erectile function （ IIEF-5 ） as a method to differentiate the causes of vasculogenic erectile dysfunction （ED）. Methods： In all, 103 ED patients （ mean age 46.8 ± 18.7） were reviewed by IIEF-5. Penile blood flow was also assessed in each patient after an intracavernosal injection （ICI） and audio-visual sex stimulation by duplex Doppler ultrasonography. The ^99mTc-^113mIn dual radioisotope test was performed to confirm specific vascular causes in the vasculogenic ED cases. Kruskal-Wallis TEST was employed to compare the scores of IIEF-5 with the results of ICI, duplex Doppler ultrasonography and the ^99mTc-^113mIn dual radioisotope test. Results ： Of the total number of ED cases, 37 （37/103, 35.9% ） were nonvasculogenic, 18（ 18/103, 17.5% ） arteriogenic, 35 （35/103,34.0%） venogenic and 13 （ 13/103, 12.6% ） combined vasculogenic. There was no significant difference in the IIEF-5 scores either between the vasculogenic group and the non-vasculogenic one （ P = 0.253） or among different groups of the vasculogenic ED patients. Conclusion ： IIEF-5 cannot be used as a tool for differential diagnosis of vaschlogenic ED, or to compare its specific vascular causes, nor can the scores of IIEF-5 reflect penile vascular conditions. Natl J Androl,2007,13 （2） ：118-121