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围生期甲状腺功能低下对仔鼠运动与学习记忆的影响 被引量：4

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摘要 甲状腺激素对中枢神经系统的发育至关重要，人类围生期甲状腺功能低下引起智力、神经功能及代谢过程的永久性改变。本课题组前期研究发现围生期甲状腺功能低下仔鼠海马神经元凋亡增加。由于海马结构是调节行为、学习记忆的重要神经解剖学基础。因而，进一步对21及50日龄甲低仔鼠运动、行为情感及学习记忆的改变进行了探讨。
作者 黄新文 李筠 季钗 杨荣旺 赵正言
机构地区 浙江大学医学院附属儿童医院儿童保健科
出处 《中华儿科杂志》 CAS CSCD 北大核心 2007年第3期221-222,共2页 Chinese Journal of Pediatrics
基金 浙江省重点科技项目(021107597)
关键词 甲状腺功能低下 学习记忆 围生期 中枢神经系统 海马神经元凋亡 甲状腺激素
分类号 R714.7 [医药卫生—妇产科学]
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参考文献9

  • 1黄新文,赵正言,季钗.甲状腺功能低下对新生期大鼠海马神经元凋亡及Bcl-2、Bax基因表达的影响[J].中华儿科杂志,2005,43(1):48-52. 被引量：11
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二级参考文献10

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共引文献10

同被引文献40

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二级引证文献5

中华儿科杂志
2007年 第3期

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