预防冠心病 Rose的全人群防治原理在21世纪仍然可以应用吗?
Preventing coronary heart disease Does Rose's population prevention axiom still apply in the 21st century?
摘要
Manuel和他的同事报道了他们如何评估三种针对加拿大人群的降脂策略的有效性（见本期第25，44页）。。其中“全人群”策略设想使整个人群的血胆固醇水平下降2％，冠心病死亡下降2．7％。另外两个策略是以患者为基础的，设想通过给冠心病高危患者服用他汀类药物可以使这些人的危险下降27％。“单一危险因素”策略是针对血胆固醇水平大于6．2mmol／L的患者；而“基线危险”策略是针对那些5年冠心病危险大于15％的患者，不考虑胆固醇水平高低。
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