麻醉大鼠左心室插管新方法

NEW METHOD OF LEFT VENTRICULAR INTUBATION IN ANAESTHETISED RATS

目的:探索在0.014’’经皮冠状动脉(PTCA)指引导丝引导下行大鼠左心室插管的方法。方法:30只Wis-tar大鼠,先后在PTCA导丝引导经右侧颈外动脉,左侧颈外动脉插管至左心室并行血流动力学测定。结果:30只大鼠成功完成一次左心室重复插管,27只大鼠完成重复插管。结论:PTCA指引导丝引导下左心室插管安全并可重复操作。

Aim： To search for a new method of left ventricular intubation in rat. Methods： The wire of percutaneous transluminal coronary angioplasty（PTCA） was put into carotid artery through external carotid artery. Then supported by guide wire, the PE50 tube was advanced into left ventricle. Results： Left ventricular intubation with PTCA guide wire could be performed in 30 rats and successfully repeated in 27 animals. Conclusion： The new left ventricular intubation technology in rats is simple and provides a reproducible method.