300例中晚期原发性支气管肺癌血瘀证分布规律的调查研究

Investigation of Distributing Characteristics of Blood Stasis Syndrome on 300 Cases of Advanced Stage Lung Cancer Patiens

目的对中晚期原发性支气管肺癌血瘀证分布规律进行调查研究。方法为Ⅲ与Ⅳ期原发性支气管肺癌患者填写《原发性支气管肺癌证型规律调查表》,观察血瘀证在中晚期原发性支气管肺癌中的分布规律。结果随着中晚期原发性支气管肺癌病理类型恶性程度增高,分化程度减低,肝转移、对侧肺转移、骨转移、锁骨上淋巴结转移等的发生,血瘀证构成比有增高的趋势。结论肺癌血瘀证有其独特的特点,对肿瘤专科甚至肺癌专病都应建立能反映其疾病本身特点的血瘀证诊断标准,以更好地指导临床诊断、疗效评价以及中药新药的临床试验。

Objective To investigate the distributing characteristics of blood stasis syndrome on 300 cases of advanced stage lung cancer patiens. Method Through filling in the table-syndrome of distributing characteristics of primary pulmonary carcinoma for stage Ⅲ and Ⅳ patients, the distributing characteristics of blood stasis syndrome in advanced lung cancer patiens were observed. Result The constituent ratio of blood stasis syndrome increased significantly following the worse patho-typing degree, the cell differentiation degree, the occurrence of hepatic metastasis, opposite pulmonary metastasis, osseous metastasis and troisier sign. Conclusion The syndrome of blood stasis of lung cancer has the distinct feature. Accordingly, the diagnostic standard which can be qualified of syndrome of blood stasis should be established. Only in that way can we guide the clinical diagnosis, the evaluation of therapeutic effect and the clinical trial of new drug of TCM preferably.