福州市区代谢综合征情况的调查

Prevalence of Metabolic Syndrome in Urban Area of Fuzhou

目的应用国际糖尿病联盟(IDF)的诊断标准定义代谢综合征(MS),调查研究福州市区2202名体检人员中MS及其相关疾病的患病情况,为有效防治此类疾病,降低心、脑血管疾病的风险提供依据。方法对2202名参加健康体检人员进行问卷调查,同时测量人体基本参数如血压、身高、体质量等,并进行血脂、血糖、尿酸、血清胰岛素等检查。研究分析MS及其不同组成成分的检出情况及其性别、年龄差异,并研究影响MS发生、发展的危险因素。结果(1)本次调查共有MS328例,所占比例为:14.9%。(2)女性MS、中心性肥胖、低高密度脂蛋白胆固醇血症比例高于男性,而男性高血压、高三酰甘油血症、脂肪肝、高尿酸血症、空腹血糖过高的比例高于女性。其差异均具有非常显著意义(P<0.01)。(3)随着年龄的增高,MS及其5种诊断指标的比例呈上升趋势。(4)糖尿病家族史、吸烟、年龄、性别、高血压家族史、饮食习惯(高盐、高脂肪、高热量饮食)、职业(脑力劳动为主)、缺乏体育锻炼是MS的危险因素。(5)空腹血糖是MS5项诊断指标中最强的指标。结论MS发病率较高,且随年龄增长逐渐增高。MS受到多种因素的影响,应加强对中年以上人群危险因素的监测,采取综合措施及早对MS进行干预和控制,以预防心血管病的发生。

Objective To investigate the prevalence of metabolic syndrome（MS） and its related diseases in urban area of Fuzhou. Methods Questionnaire were conducted in the 2202 apparently healthy people regarding their height, weight, waist circumference（WC）. BP, lipids, glucose （PG）, uric acid （UA） and serum insulin were determined. The metabolic syndrome was diagnosed according to the criterion of IDF （2005）. Results There were 328 people （14.9%）meet the criterion of MS. The prevalence rate of MS, central obesity and reduced HDL cholesterol was higher in woman than that in men; however, the prevalence of hypertension, hypertriglyceridemia, fatty liver, hyperuricemia and impaired fasting plasma glucose in man was higher than that in woman （ P〈0.05 ）. The prevalence of MS and its five components increased with increasing age. Family history of diabetes, smoking, age, sex, habitual diet （high salt, high-fat and high calorie diet）, job （mental labour） and lack of exercise were risk factors of MS. Fasting plasma glucose was the strongest factor in the five components. Conclusion The prevalence of the metabolic syndrome in this group was increased with increasing age. Monitoring of the risk factors and comprehensive measures of intervention should be strongly advocated among middle-aged and old people.