云南省2002-2004年不明原因心源性猝死事件流行病学和临床特征分析

Investigation and analysis on the incidence of ＂Yunnan unknown-cause sudden cardiac death＂ during 2002- 2004

目的分析2002-2004年云南不明原因心源性猝死事件流行病学和临床特征。方法对2002-2004年所有云南不明原因心源性猝死报告病例进行现场调查，利用描述流行病学方法，总结流行病学、临床调查和实验室检查结果，分析其特点。结果2002-2004年共报告64例死亡病例和18例同发病例，事件分布在12个县的23个自然村。以自然村为单位发病率为1．83％，死亡率为1．51％，病死率为78．1％。91．3％的病区村位于山区和半山区，7-8月的病例数占总病例数的93．94％，15～50岁组的发病者为59．8％，64．63％的病例具有家庭聚集性，89．02％的病例具有村庄聚集性。大多数病例的病程很短，病程在24h内的患者主要症状有恶心、呕吐、头昏、晕厥、乏力、胸痛和气促等。结论病例分布具有高度的时间和空间聚集性；死亡病例主要表现为心源性猝死。

Objective To understand the epidemiologic and clinical characteristics of the ＂Yunnan unknown-cause sudden cardiac death（ YUSCD）＂. Methods Cases of YUSCD occurred in 2002 - 2004 were investigated with cross-sectional study. Clinical manifestation was observed and analyzed. Results The YUSCD areas were mountainous and most of the YUSCD cases appeared between June and August. Most of the YUSCD cases were young farmers and showed family/village clustering nature. Most of the patients died quickly with only few recovered. The overall incidence of YUSCD was 1.83% with mortality as 1.51%. The fatality rate of YUSCD appeared to be 78.1%. Conclusion The YUSCD cases had a clustering feature along with time and area. The clinical manifestation of YUSCD could not be specifically identified, making the clinical diagnosis and treatment difficult when practicing in the fields that called for further studies on epidemiology, clinical work and etiology.