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失巢凋亡在As斑块破裂中的作用及机制 被引量：9

Anoikis in rupture of atherosclerotic plaque
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摘要 失巢凋亡是一种特殊形式的细胞程序性死亡,不仅参与了机体组织自身平衡的调节,而且还参与了许多病理过程的发生,如动脉粥样硬化(atherosclerosis,As)、急性冠脉综合征、心力衰竭、动脉瘤和肿瘤等。该文综述了失巢凋亡在As斑块不稳定性和破裂中的作用及机制。 Anoikis is a special programmed cell death and plays important roles in both physiological regulation and pathogenesis of many diseases, including atherosclerosis, acute coronary syndrome, cardiac failure, aneurysm and tumors. This review focuses on the association of the anoikis with instability and rupture of atherosclerotic plaque.
作者 刘娜 刘俊田
机构地区 西安交通大学医学院药理学系
出处 《中国药理学通报》 CAS CSCD 北大核心 2007年第3期298-301,共4页 Chinese Pharmacological Bulletin
关键词 失巢凋亡 动脉粥样硬化斑块 血管平滑肌细胞 细胞外基质 细胞外周基质 基质金属蛋白酶 anoikis atherosclerotic plaque vascular smooth muscle cell extracellular matrix pericellular matrix matrix metalloproteinase
分类号 R-05 [医药卫生] R329.24 [医药卫生—人体解剖和组织胚胎学]
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参考文献18

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二级参考文献25

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共引文献50

同被引文献116

引证文献9

二级引证文献175

中国药理学通报
2007年 第3期

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