血液透析患者认知功能状况及影响因素调查分析

Survey on Cognitive Function of Hemodialysis Patients and Influential Factors

目的探讨血液透析患者的认知功能及其影响因素。方法应用简易智能状态检查量表对39例血液透析患者进行认知功能评估,并与正常人群对照。应用多元逐步回归分析筛选影响患者认知功能的因素。结果观察组简易智能状态检查量表得分比对照组低,差异有统计学意义(P<0.05)。多元逐步回归分析显示:血液透析患者的认知功能与血红蛋白、Kt/v值呈正相关,与患者尿素氮水平呈负相关。结论血液透析患者的血清血红蛋白越低、尿素氮越高、Kt/v值越低,其认知功能减退越严重,同时应参考肌酐、血钠浓度、血钙浓度等因素。通过了解血液透析患者认知功能及其影响因素,采取相应的护理,提高患者的生活质量。

Objective To explore the status quo of cognitive function of hemodialysis patients and influential factors. Methods Cognitive function of hemodialysis patients were investigated with MMSE and compared with the normal people. Influential factors of cognitive function were analyzed by multiple stepwise regression. Results The score of MMSE in observation group was lower than that in control group, which showed significant differences （P〈0.05）. The analysis of multiple stepwise regression showed that cognitive function had positive relationship with hemoglobin and Kt/v and negative relationship with urea nitrogen. Conclusion Low hemoglobin, high urea nitrogen and low Kt/v can decrease the cognitive function of patients. Creatinine, Serum Sodium and serum calcium should also be taken into consideration. Through analyzing cognitive function of hemodialysis patients and influential factors, nurses can take some pertinent measures and improve patients＇ quality of life.