不同冲洗液冲洗腹部切口预防切口感染效果分析

Effects of Intraoperative Irrigation with Different Solutions on Prevention of Incision Infection after Laparotomy

目的探讨术中不同冲洗液冲洗对腹膜炎手术病人腹部切口感染的预防效果。方法150例急性弥漫性腹膜炎需行急诊手术病人,按入院手术先后顺序随机分为3组,分别使用生理盐水、0.5%聚维酮碘液、0.5%甲硝唑溶液冲洗腹部切口,比较3组患者术后腹部切口感染发生率。结果3组术后切口感染发生率差异有统计学意义(P<0.05),甲硝唑组和聚维酮碘组术后切口感染发生率明显低于生理盐水组。3组术后切口甲级愈合率比较,差异有统计学意义(P<0.05),生理盐水组的切口甲级愈合率明显低于聚维酮碘组和甲硝唑组。结论对于急性弥漫性腹膜炎手术病人,0.5%甲硝唑和0.5%聚维酮碘溶液冲洗切口预防术后切口感染效果优于生理盐水。

Objective To evaluate the effect of intraoperative irrigation with different solutions on prevention of incision infection after laparotomy. Methods 150 patients of acute peritonitis were divided into 3 groups at random, with each having 50 patients and their abdominal incision being flushed by physiological saline solution （group A）, 0.5% povidone iodine liquid （Group B） and 0.5% metroidazole （Group C） respectively. The rate of abdominal incision infection was comparatively analyzed. Results The rate of abdominal incision infection in group B and C were much lower than those of group A. There were significant differences （P〈0.05）. The rate of abdominal incision healing in group A was much lower than those of group B and C （P〈0.05）. Conclusion 0.5% povidone iodine liquid and 0.5% metronidazole have obviously preventative effects on the incision infection after laparotomy, and they are better than saline solution.