原发性醛固酮增多症功能诊断试验可靠性分析

Analysis of functional tests in the diagnosis of primary aldosteronism

原发性醛固酮增多症是最常见的导致继发性高血压的病因之一，在高血压人群中发病率高达10％-18％。在原发性醛固酮增多症的诊断中，功能诊断非常重要。目前临床常用的功能试验有血醛固酮／肾素比值的测定、静脉盐水滴注抑制试验、24h尿醛固酮及其代谢物的测定以及开博通试验等。本文将对此类功能试验的诊断可靠性作一综述。

Primary aldosteronism is one of the commonest form of secondary hypertension with an approximate prevalence of 10% - 18% in the patients with hypertension. Functional tests including plasma aldosterone and renin ratio, the saline infusion test, 24 h urinary aldosterone metabolites and eaptopril suppression test are essential for making diagnosis of primary aldosteronism. This paper reviews the reliability of these functional tests.