摘要
自身免疫性垂体炎是一种罕见的内分泌疾病,多发生于妊娠或产后。其发病机制不明,临床表现多变,主要包括垂体压迫、腺垂体功能减退症、尿崩症和高催乳素血症等相关症状。治疗目的主要是减小垂体肿块的大小和(或)替代有缺陷的内分泌功能。多数患者需要长期使用激素替代治疗。
Autoimmune hypophysitis is an unusual inflammatory lesion that is caused by autoimmune destruction of the pituitary gland, usually occurring during pregnancy or post-partum, The pathogenic mechanism is not clear. The clinical presentations of autoimmune hypophysitis comprises of four categories of symptoms: sellar compression, hypopituitarism, diabetes insipidus and hyperprolactinemia. The treatment purpose includes: reducing the size of the pipuitary mass and/or replacing the defective endocrine function. Most patients required longterm replacement with hormones.
出处
《国际内分泌代谢杂志》
2007年第2期130-132,共3页
International Journal of Endocrinology and Metabolism
关键词
自身免疫性垂体炎
临床表现
诊断
治疗
Autoimmune hypophysitis
Clinical presentations
Diagnosis
Treatment