不孕不育者生殖道淋球菌、沙眼衣原体和解脲支原体的检测结果分析

Analysis of detection results of Neisseria gonorrhoeae,Chlamydia trachomatis and ureaplasma urealyticum in infertility

目的了解在不孕不育患者中生殖道淋球菌(NG)、沙眼衣原体(CT)、解脲支原体(UU)感染的情况。方法应用实时荧光定量PCR方法对465例不孕不育患者生殖道3种病原体基因进行定量测定。结果阳性检出268例,总阳性率为57.64%,其中UU的阳性检出率最高,占43.87%;重叠感染中以UU+CT的阳性检出率最高,占3.44%。结论不孕不育患者生殖道中3种病原体感染率不尽相同,尤以UU感染率最高,是造成不孕不育的重要原因。

Objective：To investigate the infection of Neisseria gonorrhoeae （NG）, Chlamydia trachomatis （CT） ＆ ureaplasma urealyticum（UU） in 465 infertility. Methods ： Neisseria gonorrhoeae（NG）, Chlamydia trachomatis （CT） ＆ ureaplasma urealyticum（UU） of gential tract were quantitatively detected with Fluorescence Quantitative PCR from patients of infertility. Results ： The positive rate of UU is highest in single infection in infertility（43.87% ）and UU ＋ CT is highest in mixed infection in infertility（3.44% ）respectively, the total positive rate was 57.64 % （268 cases）. Conclusion：There were significant differences in positive rate of NG,CT and UU in infertility. The infection rate of UU is highest. It＇s the important agent in infertility.