2Zhu KJ,Zhang JX,Wang C,et al.Preparation and in vitro release behavior of 5-fluorouracil-loaded microspheres based on poly(L-lactide)and its carbonate copolymers[J].J Microencapsul,2003,6:731～739.
7Endoh H,Kawagchi T,Seki T,et al.Controlled release of 5-fluoro-2'deoxyuridine by the combination of prodrug and polymermatrix[J].Chem Pharm Bull (Tokyo),1991,39(2):458～464.
8Hideki M,Masao K,Hirofumi T,et al.Further apphcation of a modified spontaneous emulsification solvent diffusion method to various types of PLGA and PLA polymers for preparation of nanopartieles[J].Powder Technology,2000,107:173～179.
9Ahmad AI-Maaieh,Douglas R Flanagan.Salt and cosdvent effects on ionic drug loading into microspheres using an O/W method[J].J Control Release,2001,70:169～181.
10Zhu KJ,Jiang HL,DU XY,et al.Preparation and characterization of hCG-loaded polylactide or poly (1actide-co-glycolide) microspheres using a modified water-in-oil-in-water(w/o/w) emulsion solvent evaporation technique[J].J Microencapsule,2001,18(2):247～260.
5Godfried OA,James A,Hosmin A.Method of evaluation of sustained release microsphere formulations using the open chemostat system[J].Inter J Pharm,1995,122:9-15.
6Godfried OA,James A,Hosmin A.Effectiveness of ciprofloxacin microspheres in eradicating bacterial biofilm[J].J Control Release,1999,57:151-159.
7Matrinez B,Lairion F,Pena MB,et al.In vitro Ciprofloxacin release from poly(lactide-co-glycolide)microspheres[R].Microencapsulation,1997,14(2):155-161.
8Owusu-Ababio G,Rogers JA,et al.Efficacy of sustained release ciproxacin microspheres ahaindt device-associated Pseudomonas aeruginosa biofilm infection in a rabbit peritoneal model[Z].J Med Microbiol,1995,43(2):368-376.
9Liu Y,Deng X.Influences of preparation conditions on particle size and DNA-loading efficiency for poly(DL-lactic acid-polyethylene glycol) microspheres entrapping free DNA[J].J Control Release,2002,83(1):147-155.
