罗氏海盘车中两个新的脑苷类化合物——罗氏脑苷B和罗氏脑苷C

Rollcerebroside B and Rollcerebroside C:New Cerebrosides from Marine Animal Asterias rollestoni Bell.

采用硅胶柱色谱、凝胶柱色谱、制备HPLC等手段,从海洋生物罗氏海盘车(Asterias rollestoni Bell.)中分离得到两个化合物,利用理化和波谱分析方法鉴定为2-(2′R-羟基-十五碳酰胺)-3-羟基-(2S,3R)-二十二烷1-O-β-D-葡萄吡喃糖苷(1)和2-{2′-羟基-(2′R,14′Z)-二十三碳烯酰胺}-3-羟基-(2S,3R,6E)-十五碳烯1-O-β-D-葡萄吡喃糖苷(2),它们都是未见报道的新化合物,分别命名为罗氏脑苷B和罗氏脑苷C。

Two new compounds were isolated by chromatography from Aster/as rollestonl Bell. and identified by spectroscopic analysis and chemical reactions as 1-O-β-D-glucopyranosyl-（ 2S,3R ）-2-（ 2＇R-hydroxypentadecanoylamino ）- docosane-1,3-dlol （ roUcerebroside B,1 ） and 1-O-β-D-glucopyranosyl-（ 2S,3R,6E ）-2-[2＇-hydroxy-（ 2＇R,14＇Z ）- tficosenoylamino]-6-pentadecene-1,3-diol （rollcerebroside C,2 ）.