镧、铈、氟离子对胶原酶分解牙骨质胶原作用的影响

The influences of lanthanum, cerium and fluorine ions to the activity of collagenase degrading cemental collagens

作者对在胶原酶分解人离体牙根面胶原的过程中微量元素湖（La3+）、铈（Ce3+）及氟（F）等对溶组织梭状芽胞杆菌胶原酶（CHC）活性的影响进行了研究。结果表明La3+较Ce3+、F具有更明显地抑制CHC活性的作用，提示在根龋防治中La3+不失为一种有应用前景的微量元素。文中还对La3+、Ce3+等对胶原酶的作用机制进行了探讨。

The influences of trace elements lanthanum, cerium and fluorine to the ac-tivity of clostridium histolyticum collagenase (CHC) during the period of CHC degrading thecemental root collagen in vitro is studied. The results reveal that La3+ can significantly inhibitthe activity of the CHC than Ce3+ and F. Therefore it suggests that lanthanum may be usedas a new kind of element in preventing root caries. The mechanisms of above functions are also discussed.