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化学消融术治疗肥厚梗阻型心肌病的临床评价 被引量:1

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摘要 目的探讨经皮腔内室间隔消融术治疗肥厚性梗阻型心肌病(HOCM)的疗效及其并发症发生情况。方法12例肥厚梗阻型心肌病患者接受经皮腔内室间隔消融术,观察手术前后参数变化及并发症的发生。结果10例手术成功。左室流出道压力阶差由术前的77.3±3.2mmHg下降至术后的33.8±7.5mmHg,收缩期二尖瓣前向移动均从术前阳性转为术后的阴性,室间隔厚度由术前的29.0±1.4mm降至术后的25.5±1.3mm,左室后壁厚度术前为12.5±2.4mm术后为12.0±2.2mm。心肌酶均明显升高呈急性心肌梗死的动态演变。患者临床症状减轻,听诊心脏杂音较术前减轻Ⅰ~Ⅱ级。10例均出现各种心律失常。失败2例中1例在预阻断时出现心脏骤停;另1例出现急性前壁、下壁心肌梗死,持续室速、间歇高度房室传导阻滞及右心衰,植入永久性DDD起搏器。结论肥厚梗阻型心肌病化学消融术是治疗HOCM的一种新的介入技术,其术中及术后可发生多种并发症,对心源性猝死的影响需要长期观察。选择恰当的一支或多支间隔支动脉行化学消融,提高技术熟练性,加强监护,是减少并发症的关键。
出处 《心脑血管病防治》 2007年第1期23-24,共2页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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