中药饲料添加剂对断奶仔猪抗氧化功能的影响

Effect of Chinese herb additives on antioxidant status of weaned piglets

选取胎次相近、日龄相同的杜-长-大哺乳仔猪16窝,随机分为4组,前3个处理组在相同的基础日粮中分别添加中药饲料添加剂Ⅰ(4 kg.t-1)、中药饲料添加剂Ⅱ(4 kg.t-1)、金霉素(70 g.t-1)和杆菌肽锌(30 g.t-1).于仔猪断奶前3 d、断奶后1、4、7、14、28 d采血,对抗氧化指标进行分析,研究中药饲料添加剂对断奶仔猪抗氧化功能的影响.结果表明:断奶后1 d,各组仔猪血清总抗氧化能力(T-AOC),超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)活性与断奶前相比均降低,而丙二醛(MDA)含量较断奶前升高;整个试验期间,2个中药组血清T-AOC,SOD、GSH-Px、CAT活性始终较抗生素组和对照组高,MDA含量始终低于抗生素和对照组.可见中药饲料添加剂能改善仔猪机体自由基清除酶类的活性,增强机体的抗氧化能力.

Sucking piglets in 16 litters which had similar fetals and farrowing dates were randomly divided into four groups, three treatments were added with traditional Chinese herb feed additives Ⅰ（4 kg·t^-1） , traditional Chinese herb feed additives Ⅱ （4 kg·t^-1） and Chlortetracycline （70 kg·t^-1） and bacitracinzinc （30 kg·t^-1 ） in the same basic dietary, respectively. The blood samples were taken from the vena cava 3 days before weaning and 1,4, 7, 14, 28 days post weaning and measured to study the effect of Chinese herb feed additives on antioxidant status of weaned piglets. The results were as follows ： A day after weaning, the activity of serum superoxide dismutase （ SOD）, glutathione peroxidase （ GSH-Px ）, catahse （ CAT）, total antioxidative capacity （T-AOC） in piglets decreased, and the content of serum malonaldehyde （MDA） increased. Compared with antibiotics group and control group, the activity of serum SOD, GSH-Px, CAT and T-AOC in two Chinese herb groups were higher and the contents of serum MDA were lower during experimental period. It can be concluded that Chinese herb feed additives could improve antioxidant status of weaned piglets.