卵泡穿刺治疗PCOS所致不孕症

Treatment of ovarian follicle puncture in infertile women with polycystic ovary syndrome

目的：针对PCOS促排卵中出现的多卵泡发育及排卵障碍，采用穿刺卵泡技术治疗不孕症。方法：使用HMG／HCG促排卵共31个周期，阴道B超监测卵泡发育，给予多卵泡发育患者采用刺破卵泡4～8个，吸出多余卵泡，同时行AIH或指导前一天晚上同房。结果：31个周期中，当月临床妊娠5例，妊娠率16．12％。术后半年内再次促排卵自然妊娠3例，总妊娠率25．80％。结论：对于PCOS患者在促排卵过程中出现多卵泡发育和排卵障碍，采用卵泡穿刺技术是一个有效且安全的方法。

Objective： To increase the pregnancy rate after ovulation and an ovulation by follicle puncture. Methods： Tirty -one cycles were enrolled for ovulation induction by HMG/HCG. Follicles development was monitored by transvaginal ultrasonography. There were multiple follicles development in all 31 cycles, which were accepted the operation of follicle puncturing. Drilling 4 to 8 big follicles and aspi- rating the other small follicles. All the 31 cycles were followed by intrauterine insemination or making love last night. Results： Five patients gained clinical pregnancy in the treatment cycle. The pregnancy rate was 16. 12%. Three patients gained pregnancy by another ovulation induction within half year. The total clinical pregnancy rate was 25.80%. Conclusion： The operation of follicle puncturing is an effective and safe method for treating PCOS induced infertility when multiple follicles development and anovulation.