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清道夫受体与动脉粥样硬化 被引量:11

Scavenger receptor and atherosclerosis
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摘要 近年来对动脉粥样硬化的研究表明,清道夫受体在其发生发展中起着极其重要的作用。本文重点综述了目前研究较多的A类和B类清道夫受体的结构、功能、表达与调控及其在动脉粥样硬化中的作用,并对其他与单核-巨噬细胞源泡沫细胞形成有关的清道夫受体作一简要介绍。 Current researches suggest that scavenger receptor play an important role in the development of atherosclerosis. In this review, the structure, function, expression and regulation of scavenger receptor A/B and their role in atherosclerosis are discussed; furthermore, other scavenger receptors which involved in the monocyte/macrophage derived foam cell are also discussed.
出处 《同济大学学报(医学版)》 CAS 2007年第1期96-99,108,共5页 Journal of Tongji University(Medical Science)
基金 国家自然科学基金资助项目(30671969)
关键词 动脉粥样硬化 巨噬细胞 清道夫受体 低密度脂蛋白 atherosclerosis macrophage scavenger receptor low density lipoprotein
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参考文献19

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二级参考文献27

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